USB standard cables work cross-generationally between 1.1 and 2.0.
The MSI 945 Neo5 motherboard does not have widely reported USB problems, but it does have problems with its included BIOS software which can cause USB problems. The problem can also come from a loose connection or an attached device.
BIOS Update
The 945 Neo5's pre-installed Basic Input/Output System is known to cause problems with its interaction with other hardware. MSI has resolved the majority of the problems over BIOS revisions. You can try to resolve the USB problems by downloading and installing the latest version of BIOS from MSI's website.
USB Cable Not Connected
If you are experiencing problems with the USB ports on the computer case but not the ports on the back of the computer you probably have a loose or disconnected USB cable. The cable attached to the on-case USB ports connects to the 945 Neo5's JUSB ports. The ports can be found near the center of the motherboard on the bottom when it is mounted upright. Do not connect external Firewire connections to these ports.
Device Problems
The problem could be with the USB device. Some USB devices need their drivers installed before they will work. Other devices may need multiple ports for power reasons. Verify that the correct and updated device drivers are installed and that the device is properly connected to the USB port.
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